Updated: 11 February 2010

EU funding of diabetes and obesity research

DG Research FP7 projects
DG Research FP6 projects
DG Research FP5 projects
DG Health and Consumer Protection



This list is not exhaustive
***Project highly specific to diabetes research

7th Framework Programme (2007-2013)

Research Area: HEALTH-2007

ADAPT***
Adipokines as drug targets to combat adverse effects of excess adipose tissue
www.ADAPT-EU.net

BETACELLTHERAPY***
Beta cell therapy in Diabetes
http://www.betacelltherapy.org/

BETAIMAGE***
Use of innovative strategies for beta-cell imaging in diabetes mellitus

CEED3***
Collaborative European effort to develop diabetes diagnostics

CHEARTED
Gene-environment interactions in heart development

COPACETIC
COPD pathology: addressing critical gaps, early treatment and innovative concepts

DIABIMMUNE***
Pathogenesis of type 1 diabetes - testing the hygiene hypothesis
http://www.alphagalileo.org/ViewItem.aspx?ItemId=5945&CultureCode=en
http://www.diabimmune.org/

DIAMAP***
A Road Map for European Diabetes Research
www.DIAMAP.eu

DIAMARK***
Sensory and biomechanical markers in diabetic neuropathy of the gut. Basic investigations and new approaches for treatment

DIAPREPP***
DIAbetes type 1 PRediction, Early Pathogenesis and Prevention
http://www.diaprepp.eu

DMIOL***
Diabetes type 1 prediction, early pathogenesis and prevention


ENCITE
European Network for Cell Imaging and Tracking Expertise

EURADRENAL
Pathophysiology and natural course of autoimmune adrenal failure in Europe

GIPIO
Gastro-intestinal peptides in obesity

ICREL
Impact on clinical research of European legislation
http://www.efgcp.be/icrel

MEDCHAMPS***
Mediterranean studies of cardiovascular disease and hyperglycaemia: analytical modelling of population socio-economic transitions
http://research.ncl.ac.uk/medchamps/

MITIN***
Integration of the system models of insulin signalling and of mitochondrial function and its application in the study of complex diseases
http://www.mitin-fp7.eu/

PREPOBEDIA***
Novel Prep1-Dependent Transcriptional Networks in the Control of Insulin Sensitivity
http://www.prepobedia.org/

REPROBESITY
Search for new therapeutic agents against complicated obesity by reprofiling existing drugs
http://www.reprobesity.eu/

SYBILLA
Systems biology of T-cell activation in health and disease
http://www.sybilla-t-cell.de/

SYSKID
Systems biology towards novel chronic kidney disease diagnosis and treatment

TOBI
Targeting OBesity-driven Inflammation
http://www.tobi-project.eu/


Research Area: FP7-People Marie Curie Action

ACTIVEAGING
The effect of physical activity on muscle biology and health in statin-treated older individuals

ADIBET
The role of adipose tissue in obesity: beta cell crosstalk

ADPROGRES
Alzheimer disease progression: Molecular studies of Abeta amyloid peptides aggregation and trafficking in neuronal cells

BMP 8B THERMOGENESIS
Role of bone morphogenic protein 8b (BMP8b) in thermogenesis

CD49D IN DIABETES
Role of the alpha4 integrin (CD49d) in type-1 diabetes mellitus prevention and treatment

CX43-CRF
Implication of connexin 43 in chronic renal failure

CIRCADIAN REGULATION***
Circadian regulation in the control of insulin and glucagon release and its role in type 2 diabetes

DIABETIC EMBRYOPATHY***
Molecular Mechanisms in Diabetic Embryopathy

ENG-LEA***
Trends in hospital admissions for lower extremity amputations in people with and without diabetes in England, 1996-2005

FUNGENCEL
Functional genomics of fatty acid desaturases in caenorhabditis elegans

HASKODIABETES***
Adenosine receptors in diabetes

HEALTHY FOOD FOR LIFE
Supporting healthy lifestyles in the Mediterranean Area

HYPOTHALAMIC T3
The role of hypothalamic thyroid hormone in the neuroendocrine regulation of appetite, energy balance and glucose homeostasis

IMSCIV
Immunogenicity of mesenchymal stem cells in vivo

INSULIN SECRETION***
Regulation of glucose-stimulated secretory vesicle mobilisation in pancreatic beta-cells

IRGENOMICS***
Genetical genomics of type 2 diabetes and cardiovascular phenotypes in experimental systems

LIPOGEST
Mechanisms by which interfacial layers control lipolysis on digestion

METABOLICSYNDROME***
Role of the chylomicron and HDL pathways in the development of obesity and insulin resistance

MIELT1D***
MHC Class I expression level in type 1 diabetes

NAAN***
Natural antidiabetic & anti-hypertensive drugs

NRFDIABVASC***
Role of Nrf2 transcription factor in diabetic vasculopathy, oxidative stress and inflammation

OBESITY AND IMMUNITY
Prevention of obesity-related inflammation

OXFORDWINSTON***
The effects of lineage differentiation into pancreatic beta-cells on the immunogenicity of amniotic fluid stem cells

P16 AND METABOLISM***
The role of p16INK4a in the development of obesity and insulin resistance

PHD-OB-T2D***
Study the role of oxygen sensors Prolyl Hydroxylase Domain (PHD) protein in obesity and type 2 diabetes

PREVENTION T2D***
Life style and genetic factors in prevention of type 2 diabetes

PROTEINCHARGEDENSITY
Quantitative analysis of atomic polarization and protein-ligand electrostatic interactions via charge density studies in proteins: insights from ultra-high resolution crystallography

PTPS
Spatio-temporal regulation of growth factor signaling by PTPs in living cells

SIRT1 AND DIABETES***
Identification of the genes regulated by the SIRT1 histone deacetylase and their contribution in the pathogenesis of type 2 diabetes and obesity

SMART
Small molecule antagonists of chromatin modifying enzymes for regulation of transcription, proliferation and differentiation

TRANSHESC
Generation of stable transgenic embryonic stem cell lines


Research Area: ERC-AG /-SG

ADIPODIF***
Adipocyte differentiation and metabolic functions in obesity and type 2 diabetes

ALK7***
Metabolic control by the TGF-2 superfamily receptor ALK7: a novel regulator of insulin secretion, fat accumulation and energy balance

COMBINE
From flies to humans combining whole genome screens and tissue specific gene targeting to identify novel pathways involved in cancer and metastases

CONANX
Consumer culture in an age of anxiety: political and moral economies of food

DENDROWORLD
Mucosal dendritic cells in intestinal homeostasis and bacteria-related diseases

ICEBERG***
Discovery of type 2 diabetes targets


Research Area: ICT-2007

DIADVISOR***
Personal glucose predictive diabetes advisor

HEARTCYCLE
Compliance and effectiveness in HF and CHD closed-loop management

METABO***
Controlling chronic diseases related to metabolic disorders

TAS3
Trusted architecture for securely shared services


Research Area: INFRA-2007

EATRIS
European Advanced Translational Research InfraStructure in Medicine
http://www.eatris.eu


Research Area: KBBE-2007

ETHERPATHS
Characterization and modelling of dietary effects mediated by gut microbiota on lipid metabolism







6th Framework Programme (2002-2006)

BARP+***
Development of a bioartificial pancreas for type 1 diabetes therapy

BETACELLTHERAPY***
BETACELLTHERAPY

CLINICIP***
Closed loop insulin infusion for critically ill patients

DIABESITY***
DIABESITY

DIOGENES
Diet, Obesity and Genes

EARNEST
Early nutrition programming for adult health

EUGENE2***
European Network on Functional Genomics of Type 2 Diabetes

EURODIA***
Functional genomics of pancreatic beta cells and of tissues involved in control of the endocrine pancreas for prevention and treatment of type 2 diabetes

EUROSTEMCELL
EuroStemCell's mission is to build the scientific foundations required to take stem cell technology to the clinic

EUROTHYMAIDE
Understanding of the mechanisms underlying the development of autoimmune diseases, by exploring the major biological functions of the thymus

EXGENESIS***
Health benefits of exercise: identification of genes and signalling pathways involved in effects of exercise on insulin resistance, obesity and the metabolic syndrome

HELENA
Healthy Lifestyle in Europe by Nutrition in Adolescence

HEPADIP***
Hepatic and adipose tissue in the metabolic syndrome

IDEFICS
Identification and prevention of dietary and lifestyle induced health effects in children and infants

IMMIDIAB***
Genetic susceptibility for type 2 diabetes among immigrants in Europe

LIPGENE
Diet, genomics and the metabolic syndrome: an integrated nutrition, agro-food, social and economic analysis

MOLPAGE***
Molecular phenotyping to accelerate genomic epidemiology

MUGEN
Integrated Functional Genomics in Mutant Mouse Models as Tools to Investigate the Complexity of Human Immunological Disease

PREDICTIONS***
The Identification of Risk Factors for the Development of Diabetic Nephropathy

RISET
Reprogramming the immune system for the establishment of tolerance

SAVEBETA***
Molecular pathways underlying decreased beta cell mass in diabetes mellitus
(not yet working)

TONECA***
Coordination action on the aetiology, pathology and prediction of type 1 diabetes in Europe in the 6th Frame Programme of the European Union

INTER-ACT***
A study of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes





5th Framework Programme (1998-2002)

Action LADA***
Prevalence characterisation and prevention of latent autoimmune diabetes in adults (LADA) in Europe

ADICOL
Advanced Insulin Infusion using a Control Loop

AMPDIAMET***
The cellular fuel gauge AMP-activated protein kinase: a key player in type 2 diabetes, cardiovascular disease and the metabolic syndrome?

BIOCLA
Production of CLA-enriched dairy products by natural means

CAUSES OF TYPE 2 DIABETES / EuroDiabetesGene***
Phenotypes and genes linked to insulin resistance and risk for type 2 diabetes

DIABETES PREVENTION***
Nutritional primary prevention of type 1 diabetes

DIET and OBESITY
Dietary and genetic influences on susceptibility or resistance to weight gain on a high fat diet

EU CHILDHOOD OBESITY
Childhood obesity: early programming by infant nutrition?

EUPEAH
Glucocorticoid hormone programming in early life and its impact in adult health

EURAGEDIC***
European rational approach for the genetics of diabetes complications

EURODIALE***
Optimal organisation of health care in diabetic foot disease

EUROSTARCH
Stable isotope applications to monitor starch digestion and fermentation for the development of functional foods

FACTORS IN HEALTHY EATING
Examines the causes of eating disorders and obesity

GIFT***
Genomic integrated force for type 2 diabetes

GrowBeta***
Generation and functional characterisation of neuro-endocrine cells for cellular replacement therapy

HSP for THERAPY***
Heat shock protein 60 as a novel therapeutic target for diabetes and rheumatoid arthritis

INCA
Intelligent Control Assistant for Diabetes

MONODIAB***
The blood monocyte as a tool for the prediction of type 1 diabetes

NUGENOB
Nutrient-gene interactions in human obesity: implications for dietary guidelines

NUTRIX
Early malnutrition and programming of adult degenerative diseases: experimental, epidemiological and preventive studies

OB-AGE
Obesity and disease in ageing

Pancreas Development***
Molecular mechanisms controlling pancreas organogenesis and differentiation of pancreatic cell types

PSEUDOISLET***
Generation of bioengineered pancreatic islet micro-organs for insulin replacement therapy in diabetes mellitus

RISC***
Relationship between insulin sensitivity and cardiovascular disease risk

TUNEUP
Therapeutic utlilisation of a novel enzyme with unique adhesion properties

VIRUS IN DIABETES - VIRDIAB***
Enterovirus infections as a risk factor for type 1 diabetes

You can find more details on the above mentioned projects in the "Catalogue of Community funded projects in the field of diabetes research in FP5" (Quality of Life and Management of Living Resources Programme - 1998-2002)
Catalogue
http://www.cordis.lu/life/




DG Health and Consumer Protection

2006
IMAGE
Development and implementation of a European Guideline and training standards for diabetes prevention
http://www.image-project.eu/

2005
UCID
EUropean Core Indicators in Diabetes Mellitus
http://ec.europa.eu/health/ph_projects/2005/action1/action1_2005_11_en.htm

2004
Diabetes in Europe - Prevention using Lifestyle, Physical Activity and Nutritional intervention
http://ec.europa.eu/health/ph_projects/2004/action3/action3_2004_25_en.htm

EMOB
European Mapping of Obesity Best practice
http://ec.europa.eu/health/ph_projects/2004/action3/action3_2004_21_en.htm

2003
Children, obesity and associated avoidable chronic diseases
ttp://ec.europa.eu/health/ph_projects/2003/action3/action3_2003_04_en.htm